Divalproex Sodium

Description

Introducing Divalproex Sodium Tablets by PharmAlliance International Labs

Welcome to PharmAlliance International Labs, where we are dedicated to pioneering innovative healthcare solutions to enhance the well-being of individuals worldwide. Our Divalproex Sodium Tablets are meticulously formulated to effectively manage a spectrum of neurological and psychiatric conditions, providing relief and support to patients in need. With a steadfast commitment to quality and patient care, we endeavor to deliver trusted medications that promote overall health and elevate quality of life.

Drug Classification:

Divalproex sodium belongs to the class of drugs known as anticonvulsants and mood stabilizers. Comprised of sodium valproate and valproic acid, Divalproex sodium operates by elevating the levels of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. This mechanism aids in reducing abnormal electrical activity and stabilizing mood, offering therapeutic benefits for various conditions.

Formulations:

Divalproex Sodium Tablets:

• Strength: Available in 500mg tablets.
• Product Form: Oral tablets for convenient administration.
• Packing Specs: Each pack contains 100 tablets.

Indications:

Divalproex Sodium Tablets are indicated for the treatment of:

Epilepsy: Utilized as an adjunctive therapy in managing complex partial seizures and simple and complex absence seizures.

Bipolar Disorder: Effective in treating manic episodes associated with bipolar disorder (manic-depressive illness).

Usage:

It is recommended to take Divalproex Sodium Tablets orally, with or without food, as directed by a healthcare professional. Adhering to the prescribed dosage and dosing schedule is crucial to achieving optimal therapeutic outcomes. Dosage adjustments may be necessary based on individual response and tolerability, necessitating close monitoring by a healthcare provider.

Dosage:

For epilepsy, the recommended initial dosage of Divalproex Sodium Tablets typically ranges from 10 to 15 mg/kg/day, divided into two or three doses. In the treatment of bipolar disorder, the initial dosage is generally 750 mg daily, administered in divided doses. Dosage adjustments may be made based on clinical response and serum valproate concentrations, with a maximum recommended dosage of 60 mg/kg/day.

Pharmacokinetics:

After oral administration, Divalproex sodium is rapidly absorbed, with peak plasma concentrations achieved within 4 hours. Metabolized extensively in the liver via glucuronidation and cytochrome P450-mediated oxidation, Divalproex sodium exhibits an elimination half-life of approximately 9 to 16 hours, facilitating twice-daily or thrice-daily dosing regimens.

Pharmacodynamics:

Divalproex sodium exerts its therapeutic effects by augmenting inhibitory neurotransmission mediated by GABA in the central nervous system. Through modulating neuronal excitability and inhibiting abnormal electrical activity, Divalproex sodium aids in preventing seizure propagation and mood stabilization in individuals with bipolar disorder.

Side Effects:

Common side effects associated with Divalproex Sodium Tablets may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. Additionally, adverse reactions such as drowsiness, dizziness, tremor, weight gain, hair loss, and liver function abnormalities may occur. In rare instances, more serious adverse events such as hepatotoxicity, pancreatitis, thrombocytopenia, and encephalopathy may manifest.

Trust in the efficacy and safety of Divalproex Sodium Tablets from PharmAlliance International Labs. Whether seeking seizure control or mood stabilization, our product offers a reliable solution to help individuals achieve optimal health and well-being. For further information, please visit our website or consult your healthcare provider.