Lamotrigine

Description

Introducing Lamotrigine Tablets by PharmAlliance International Labs

Welcome to PharmAlliance International Labs, where our dedication to healthcare innovation and excellence drives us to provide cutting-edge solutions for individuals worldwide. Our Lamotrigine Tablets represent a significant advancement in the management of epilepsy and bipolar disorder, offering effective symptom control and enhancing quality of life. With a steadfast commitment to quality and patient well-being, we deliver trusted medications that truly make a difference in the lives of our valued customers.

Drug Classification:

Lamotrigine belongs to the class of drugs known as anticonvulsants or antiepileptic drugs. Its mechanism of action involves stabilizing neuronal membranes and inhibiting the release of excitatory neurotransmitters, thereby reducing abnormal electrical activity in the brain. Additionally, Lamotrigine exhibits mood-stabilizing properties, making it a valuable treatment option for bipolar disorder.

Formulations:

Lamotrigine Tablets:

• Strength: Available in 50mg and 100mg tablets.
• Product Form: Oral tablets designed for easy administration.
• Packing Specs: Each pack contains 30 tablets.

Indications:

Lamotrigine Tablets are indicated for the treatment of:

Epilepsy: Used as adjunctive therapy or monotherapy in managing partial seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome.

Bipolar Disorder: Indicated for the maintenance treatment of bipolar I disorder to delay the occurrence of mood episodes (depression, mania, hypomania, mixed episodes) in adults.

Usage:

For optimal therapeutic effects, Lamotrigine Tablets should be taken orally with or without food, as directed by a healthcare professional. Adhering to the prescribed dosage and dosing schedule is crucial, with dosage adjustments made based on individual response and tolerability under close medical supervision.

Dosage:

For epilepsy:

Starting dosage: Typically initiated at 25mg once daily for the first two weeks, followed by gradual titration based on response and tolerability.

Maintenance dosage: Ranges from 100mg to 400mg daily, administered in divided doses.

For bipolar disorder:

Starting dosage: Determined by whether Lamotrigine is used as monotherapy or adjunctive therapy and concomitant medications.

Maintenance dosage: Typically ranges from 100mg to 200mg daily.

Pharmacokinetics:

Following oral administration, Lamotrigine is rapidly absorbed, with peak plasma concentrations attained within 1.4 to 4.8 hours. Extensively metabolized in the liver via glucuronidation, with renal excretion of metabolites, Lamotrigine exhibits an elimination half-life of approximately 24 to 35 hours in adults, allowing for once-daily or twice-daily dosing regimens.

Pharmacodynamics:

Lamotrigine’s therapeutic effects stem from its ability to stabilize neuronal membranes and inhibit excitatory neurotransmitter release, such as glutamate and aspartate. By reducing abnormal electrical activity in the brain, Lamotrigine aids in preventing seizures and stabilizing mood in individuals with bipolar disorder.

Side Effects:

Common side effects associated with Lamotrigine Tablets may include headache, dizziness, somnolence, nausea, vomiting, blurred vision, and rash. Rare but serious adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and aseptic meningitis have been reported. Monitoring for signs of hypersensitivity reactions, especially during initial treatment, is essential.

Trust in the efficacy and safety of Lamotrigine Tablets from PharmAlliance International Labs. Whether managing epilepsy or bipolar disorder, our product offers a reliable solution to help individuals lead fulfilling lives. For more information, please visit our website or consult your healthcare provider.